Table 1.
Exosome proteins upregulated and downregulated by radiation
| IR-upregulated proteins |
| Mode [0 < 2,4,8]: 100A11; ABP1; ACKR3; ACLY; ACTA1; ACTG1; ADAM30; ADRM1; AEN; AHNAK; AKAP8L; ANKFY1; ANXA1; ANXA11; APEH; APMAP; APOA4; APOM; ARF3; ARF4; ARHGEF6; ARMCX4; ARPIN; ARR3; ARRDC1; ASPN; ASS1; ATIC; ATP2B1; ATXN2; B4GALNT4; BCHE; BHLHE22; BNIP3L; BRD9; BSG; C1QTNF3; C1R; C4BPA; C8A; CALY; CAP1; CAPNS1; CASP12; CASP7; CCDC129; CCDC158; CCK; CCT2; CCT4; CCT6A; CCT7; CCT8; CD151; CD63; CD81; CD82; CDC42BPB; CENPF; CFAP65; CFHL5; CFI; CFL1; CHD4; CLIC1; CMTM2; CNOT9; COG2; COG7; COL12A1; COL17A1; COL5A2; COL6A2; COL6A3; COL6A5; COLEC10; COLEC11; COPB1; COPS2; CPB2; CSF2RB; CSRP1; CTR9; CUL5; CUX1; CYP21A2; DARS; DDIAS; DDX21; DGKZ; DHX9; DMXL1; DNAH9; DPYS; EED; EEF1A1P5; EFCAB5; EIF3C; EIF3F; EIF3L; ENO4; EPHB2; ERC2; ERCC5; ERLIN2; ESPN; ESRP2; ETNPPL; EXOC1; EXT1; F10; F13A1; FAM120A; FAM177A1; FAM3C; FAT4; FCRL6; FHAD1; FLG; FLG2; FLNA; FLNB; FMO4; FST; FUT6; FZD10; FZD2; GDPD5; GFPT1; GFRA1; GNAI2; GOLGA6L6; GPATCH11; GPC1; GPX3; GRIK4; H2AFV; HERC3; HGF; HGFAC; HIC2; HIST1H2AC; HIST1H3A; HIST1H4A; HIST2H2BF; HIST2H3PS2; HSP90AA1; HSP90AB1; HSPA8; HSPB1; HSPD1; HUWE1; IARS; IKBKE; IL1R1; ILDR2; IPO11; IST1; ITGA6; ITGB1; ITGBL1; JAK3; JMJD1C; KRT74; KRT77; KTN1; LAMA1; LAMA2; LAMA5; LAMB2; LAMB3; LAMC2; LAMP1; LIMK1; LRP2; LRP4; LRRC6; LRRC70; LTBP4; MACF1; MAPK6; MAPK8IP2; MATN2; MEGF6; MEGF8; MFGE8; MMP13; MORC4; MRC2; MROH2A; NAA16; NAP1L1; NAPA; NBR1; NCOR1; NCSTN; NDC1; NEB; NELL2; NEXN; NIPBL; NOL5A; NOS1; NOTCH1; NPTX1; NT5E; NUMA1; OMD; OR10J4; OR2A25; PAK7; PARG; PARK7; PAX6; PCSK2; PDCD6IP; PDZD2; PERP; PGM1; PHF3; PHGDH; PHKA1; PI4KB; PID1; PIGG; PIWIL1; PKM; PLCD1; PLEKHB1; PLSCR5; PLXNB2; POLI; PPM1G; PRDX1; PRDX2; PRG4; PROS1; PRSS23; PSAP; PSAT1; PSEN1; PSEN2; PSMA6; PSMC3; PSMC5; PSMC6; PSMD1; PTTG1IP; PYGB; RAB11A; RAB1A; RAB1B; RAB7A; RAC1; RAC2; RACK1; RAN; RECQL5; RGN; RGPD4; RIC8A; RNF19A; RNF6; RPL18A; RPL28; RPL30; RPL5; RPL7A; RPLP0; RPLP1; RPS18; RPS26P11; RPS27A; RPS3; RPS6; RPSA; RPTN; RRAS2; RRBP1; RTN4; RUVBL1; RYR2; S100A14; S100A2; SAP30BP; SBDS; SDC1; SERPINA5; SGCD; SHROOM2; SHROOM4; SLC1A5; SLC22A8; SLC28A2; SLC38A1; SLC38A5; SLC4A9; SLC7A1; SLC7A5; SMC5; SMCO3; SNCAIP; SORBS2; SOWAHB; SOX30; SPARCL1; SPIDR; SPOCK1; SPOCK2; SPON1; SPTBN5; SSH2; STAM; SULT2B1; SUSD5; SYCP1; SYMPK; TACSTD2; TBCD; TBCK; TBKBP1; TBR1; TCHH; TEX14; TFAP2D; TFRC; TGM6; THBD; THBS3; TIMP3; TINAGL1; TM4SF1; TM7SF3; TMPRSS6; TNFAIP2; TNFRSF19; TNKS; TOLLIP; TRIAD3; TRIML1; TROPH; TSPAN14; TSPAN9; TTC30B; TTI2; TTN; TUBA1A; U2AF1; U2SURP; UNC5CL; USP45; VIPR2; VPS4A; WBP2NL; WDSUB1; WNT7A; XPO6; XRCC5; XRCC6; ZC3H14; ZDHHC5; ZFHX3; ZFP64; ZNF25; ZNF563; ZNF671; ZNF770; ZNF804B; ZUFSP |
| Mode [0,2 < 4,8]: ABO; ANXA4; C8G; CCM2; CNGB1; COL18A1; DEFA3; F5; FBLL1; GNG12; LMNA; LRPPRC; MMRN1; NECAB2; OXCT; PRR13; QSOX1; RAB5B; RPL24; SEC14L2; SPRR2C; SRGAP3; SRI; SUPT4H1; TRPM7; TSPAN3; TTC9B; VPS37B; WWC2 |
| Mode [0,2,4 < 8]: CLDN1; CNTN4; CSMD3; DYNLL1; ETFRF1; GNG5; GUSB; KCNK1; KRT39; MAP3K7CL; MOB1B; ORAOV1; PDE4C; PGBD1; PPT1; PSMD2; RAB14; RAD51D; RBM26; RPL17; RPL36; RPS25; SET; TP53; TRIM22; UNQ3118; ZNF195 |
| IR-downregulated proteins |
| Mode [0 > 2,4,8]: ACOX3; APOA2; C1S; CASK; CIB3; COX10; CUBN; DDX58; FAM107A; FANCM; GCA; GTPBP1; IPO5; MME; PANK1; PLAT; RNF149; RPL26; RPL8; RPS14; RUVBL2; SAMD8; SETMAR; SLC34A1; SMCO2; SRL; STOX2; STRCP1; TG; THRA; TTN; ZC3H4 |
| Mode [0,2 > 4,8]: ANKRD62; BABAM1; COL9A1; HHLA1; NXF1; OAS3; SERPINB5; T |
| Mode [0,2,4 > 8]: ABI3BP; DDX41; LMCD1; LSR; PLCB4; SZT2; ZFP62 |
Presented are subsets of proteins that belong to different modes described in the text.