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. 2019 Apr 29;60(3):298–307. doi: 10.1093/jrr/rrz011

Fig. 5.

Fig. 5.

Prediction of the dose–response curve in PCa cells. Prediction of the dose–response curve by each model (A) in DU145 cells, (C) in PC3 cells and (E) LNCaP cells, shown on the log scale, and (B) DU145 cells, (D) PC3 cells and (E) LNCaP cells, shown on the linear scale. The black line with squares shows the survival data on the assumption that 0% of radioresistant cells were present, estimated by the IMK model with CSC prediction; the gray broken line with circles shows 0.01% radioresistant cells, the dark gray broken line with triangles shows 0.1% radioresistant cells, the gray broken line with inverted triangles shows 1% radioresistant cells, the black broken line with diamonds shows 10% radioresistant cells, and the gray broken line with left-pointing triangles shows 100% radioresistant cells. PCa: prostate cancer, IMK: integrated microdosimetric kinetic, CSCs: cancer stem cells.