Table 1.
Baseline Characteristics | N=26 |
---|---|
Median age, years (range) | 74 (53–87) |
Median disease duration, months (range) | 18.1 (1.4–221.4) |
Disease subtype | |
PMF | 17 (65.4%) |
PPV-MF | 8 (30.8%) |
PET-MF | 1 (3.8%) |
Lille Score | |
0 | 11 (42.3%) |
1 | 11 (42.3%) |
2 | 4 (15.4%) |
DIPSS | |
Intermediate-1 risk | 4 (15.4%) |
Intermediate-2 risk | 8 (30.8%) |
High risk | 14 (53.8%) |
Karyotype | |
Favorable | 14 (53.8%) |
Unfavorable | 7 (26.9%) |
Not available | 5 (19.2%) |
Median spleen size, cm | |
0 | 3 (11.5%) |
1–10 | 3(11.5%) |
11–20 | 13(50.0%) |
>20 | 7(26.9%) |
Median number of prior MF treatments | |
0 | 3(11.5%) |
1 | 12(46.2%) |
2 | 7(26.9%) |
3 | 2(7.7%) |
4 | 1(3.8%) |
5 | 1(3.8%) |
Prior JAK2 inhibitors | 2 (7.7%) |
JAK2V617Fallele burden(%) | |
Missing | 11 |
<50% | 2(11.87%) |
>=50% | 15(88.2%) |