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. Author manuscript; available in PMC: 2019 Nov 21.
Published in final edited form as: Bioconjug Chem. 2018 Oct 29;29(11):3691–3704. doi: 10.1021/acs.bioconjchem.8b00611

Figure 2:

Figure 2:

Schematic illustration of the 2-step Murray place exchange strategy for ligand installation. Different number densities of H3 tail ligands are controlled by the H3 tail ligand feed ratio. MUA = mercaptoundecanoic acid; K5 = 5-residue polylysine peptide; H3 = H3 tail peptide (residues 1–25)