Table III.
Effect of DMNQ on MAP kinase phosphorylation between femur and talar chondrocytes
Time (min) | Talus vs Femur pERK | Talus vs Femur p-P38 | Talus vs Femur p-JNK | Talus vs Femur p-c-Jun |
---|---|---|---|---|
Time point | Statistical test | |||
Paired t-test | Paired t-test | Paired t-test | Paired t-test | |
5 min | −0.03 (−0.34, 0.29) P = 0.85 | 0.03 (−0.12, 0.19) P = 0.64 | −0.04 (−0.15, 0.06) P = 0.36 | 0.02 (−0.23, 0.28) P = 0.85 |
10 min | −0.31 (−0.86, 0.23) P = 0.22 | 0.06 (−0.24, 0.36) P = 0.65 | −0.03 (−0.10, 0.04) P = 0.35 | −0.18 (−0.63, 0.27) P = 0.37 |
15 min | −0.06 (−0.32, 0.44) P = 0.71 | 0.03 (−0.09, 0.15) P = 0.55 | 0.00 (−0.11, 0.11) P = 0.93 | −0.06 (−0.23, 0.11) P = 0.45 |
30 min | 0.29 (—0.01, 0.58) P = 0.06 | 0.12 (−0.04, 0.28) P = 0.12 | 0.10 (−0.19, 0.38) P = 0.45 | −0.29 (−0.82, 0.23) P = 0.23 |
60 min | 0.34 (−0.32, 0.99) P = 0.26 | 0.26 (0.10, 0.42) P=0.01 | 0.44 (−0.32, 1.21) P = 0.21 | −0.25 (−0.96, 0.46) P = 0.44 |
Data presented shows mean differences, 95% CI (in parentheses) and P-values for t-tests between differences in femur and differences in talus at the corresponding time point.