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. Author manuscript; available in PMC: 2019 May 22.
Published in final edited form as: Lab Invest. 2018 Nov 23;99(4):470–482. doi: 10.1038/s41374-018-0161-1

Fig. 4.

Fig. 4

Expression of genes encoding extracellular matrix components in the skin and lungs of male saline-treated and TGF-β1-treated C57BL6/J and Nox4 knockout mice. Expression of Col1a1, Col3a1, Col4a1, and Fn in skin (a) and lung (b). The values shown are the mean (±SD) fold change levels of gene expression from each treatment group performed in triplicate for each tissue. Gene expression levels were normalized to 18S levels. Values for other samples are expressed relative to the saline-treated C57BL6/J control group which was arbitrarily set at the 100% expression level. Significance was determined by Student’s t-test. Statistical significance: ***p < 0.001