Table 2.
Distribution of the SNP rs146534657:A>G
| Race/ethnicity | No. of participants |
Single-nucleotide polymorphism | Minor allele frequency (%) |
Odds ratio vs. Caucasian (95% CI) |
|---|---|---|---|---|
| Caucasian | 3 | 3 | 1.08 | – |
| Hispanic | 40 | 41 | 4.37 | 4.05 (1.24−13.18) |
| Asian | 1 | 1 | 1 | 0.93 (0.10−9.01) |
| African-American | 0 | 0 | 0 | 0 |
| Middle Eastern | 0 | 0 | 0 | 0 |
| Others | 0 | 0 | 0 | 0 |
Distribution of rs146534657:A>G among the ethnic/racial groups. The MAF of this SNP (0.11–1.3%) per NCBI dbSNP is similar to the Caucasian participants of our cohort. The MAF of this SNP among the Hispanic participants of our cohort is significantly different.