Table 3.
Distribution of the SNP rs2230926:T>G
| Race/ethnicity | No. of participants |
Single- nucleotide polymorphism |
Minor allele frequency (%) |
Odds ratio vs. Caucasian (95% CI) |
|---|---|---|---|---|
| Caucasian | 11 | 11 | 3.96 | – |
| Hispanic | 30 | 32 | 3.41 | 0.86 (0.43−1.73) |
| Asian | 4 | 4 | 4 | 1.01 (0.31−3.25) |
| African-American | 12 | 13 | 14.44 | 3.65 (1.58−8.43) |
| Middle Eastern | 2 | 2 | 6.25 | 1.58 (0.34−7.45) |
| Others | 0 | 0 | 0 | 0 |
Distribution of rs2230926:T>G among the ethnic/racial groups. The MAF of this SNP (6.13–17.85%) per NCBI dbSNP is lower among the Caucasian participants of our cohort. The MAF of this SNP among African-American participants is significantly higher.