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. Author manuscript; available in PMC: 2019 May 22.
Published in final edited form as: Lancet Glob Health. 2017 Feb 23;5(4):e448–e457. doi: 10.1016/S2214-109X(17)30078-5

Table 3:

Parameter estimates for monthly childhood vaccinations in the Forest region, Guinea, from January, 2013, to February, 2016

BCG Pentavalent Polio Measles Yello wfever
β 95% Cl p val ue β 95% Cl p value β 95% Cl p value β 95% Cl p value β 95% Cl p value
Number of childhood vaccinations at beginning of pre-Ebola period (β0) 5752 2821 to 8682 0.0005 7498 7154 to 7841 <0.0001 6953 6380 to 7526 <0.0001 7788 7443 to 8133 <0.0001 8043 7621 to 8464 <0.0001
Average monthly change in number of vaccinations over pre-Ebola period (β1) 321 58 to 584 0.0193 93 50 to 136 0.0002 118 47 to 190 0.0025 119 53 to 185 0.0012 106 44to 167 0.0017
Average monthly change in number of vaccinations during Ebola virus disease outbreak (β2) −3048 −5879 to-216 0.0362 −1483 −2469 to-497 0.0051 −3594 −4811 to-2377 <0.0001 −1328 −2474to-l82 0.0252 −1075 −215 8 to 7 0.0514
Difference between trend in vaccinations during Ebola virus disease outbreak compared with p re-disease period (β3) −419 −683 to-155 0.0034 −313 −446 to-179 <0.0001 −108 −276 to 61 01976 −357 −483 to-231 <0.0001 −363 −488 to-238 <0.0001
Average monthly change in number of vacc i nati on s d u ri ng post-Ebola period (β4) 128 −2776 to 3031 0.928 655 −1009 to 2320 0422 76 −1145 to 1297 0.898 1024 −516 to 2565 0481 1295 −245 to 2835 0.095
Difference between trend in vaccinations during post-Ebola period compared with outbreak period (β5) −127 −328 to 73 0.2014 154 10 to 299 0.0373 −107 −262 to 47 01630 81 −27 to 189 0.1338 58 −57 to 172 0.3056
Overall trends
 Lineartrend during outbreak (β1 + β3) −99 −332 to 135 0.3899 −220 −3 63 to-77 0.0042 11 −139 to 161 0.8841 −238 −371 to-105 0.0013 −258 −391 to-125 0.0006
 Lineartrend after outbreak (β1 + β3 + β5) −226 −520 to 68 0.1251 −66 −201 to 70 0.3248 −97 −179 to-14 0.0240 −157 −249 to-65 0.0018 −200 −298 to-102 0.0004

Data are from the segmented ordinary least–square regression model. BCG=Bacille Calmette-Guerin (anti-tuberculosis vaccine). p value tests the null hypothesis that each of the coefficients is equal to zero, following the model specification and description in the methods section.