Table 3:
BCG | Pentavalent | Polio | Measles | Yello wfever | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | 95% Cl | p val ue | β | 95% Cl | p value | β | 95% Cl | p value | β | 95% Cl | p value | β | 95% Cl | p value | |
Number of childhood vaccinations at beginning of pre-Ebola period (β0) | 5752 | 2821 to 8682 | 0.0005 | 7498 | 7154 to 7841 | <0.0001 | 6953 | 6380 to 7526 | <0.0001 | 7788 | 7443 to 8133 | <0.0001 | 8043 | 7621 to 8464 | <0.0001 |
Average monthly change in number of vaccinations over pre-Ebola period (β1) | 321 | 58 to 584 | 0.0193 | 93 | 50 to 136 | 0.0002 | 118 | 47 to 190 | 0.0025 | 119 | 53 to 185 | 0.0012 | 106 | 44to 167 | 0.0017 |
Average monthly change in number of vaccinations during Ebola virus disease outbreak (β2) | −3048 | −5879 to-216 | 0.0362 | −1483 | −2469 to-497 | 0.0051 | −3594 | −4811 to-2377 | <0.0001 | −1328 | −2474to-l82 | 0.0252 | −1075 | −215 8 to 7 | 0.0514 |
Difference between trend in vaccinations during Ebola virus disease outbreak compared with p re-disease period (β3) | −419 | −683 to-155 | 0.0034 | −313 | −446 to-179 | <0.0001 | −108 | −276 to 61 | 01976 | −357 | −483 to-231 | <0.0001 | −363 | −488 to-238 | <0.0001 |
Average monthly change in number of vacc i nati on s d u ri ng post-Ebola period (β4) | 128 | −2776 to 3031 | 0.928 | 655 | −1009 to 2320 | 0422 | 76 | −1145 to 1297 | 0.898 | 1024 | −516 to 2565 | 0481 | 1295 | −245 to 2835 | 0.095 |
Difference between trend in vaccinations during post-Ebola period compared with outbreak period (β5) | −127 | −328 to 73 | 0.2014 | 154 | 10 to 299 | 0.0373 | −107 | −262 to 47 | 01630 | 81 | −27 to 189 | 0.1338 | 58 | −57 to 172 | 0.3056 |
Overall trends | |||||||||||||||
Lineartrend during outbreak (β1 + β3) | −99 | −332 to 135 | 0.3899 | −220 | −3 63 to-77 | 0.0042 | 11 | −139 to 161 | 0.8841 | −238 | −371 to-105 | 0.0013 | −258 | −391 to-125 | 0.0006 |
Lineartrend after outbreak (β1 + β3 + β5) | −226 | −520 to 68 | 0.1251 | −66 | −201 to 70 | 0.3248 | −97 | −179 to-14 | 0.0240 | −157 | −249 to-65 | 0.0018 | −200 | −298 to-102 | 0.0004 |
Data are from the segmented ordinary least–square regression model. BCG=Bacille Calmette-Guerin (anti-tuberculosis vaccine). p value tests the null hypothesis that each of the coefficients is equal to zero, following the model specification and description in the methods section.