Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 12;9(8):2158–2166. doi: 10.7150/thno.30886

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ivyspring International Publisher

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

(A) Confocal imaging of co-cultured normal cells (HepG2 cells) and cancer cells (Astrocytes cells): DAPI (Blue), GFAP (Red), Pt complex (Green), and Merge channel. (B) Schematic representation of normal cells and cancer cells population distribution from captured micrograph. (C) GFAP negative cells represent cancer cells with intense nuclear uptake. (D) GFAP positive astrocytes displayed cytosolic uptake without nuclear staining. (E) A zoom in micrograph showed Pt complex different intracellular distribution in the co-culture model from 5 cells including 1 HepG2 cell and 4 astrocytes. (F) Pt complex fluorescence analysis at nuclear and cytosol from astrocytes and HepG2 cells. Scale bars = 20 μm. Abbreviations: G2: HepG2 cells; As: Astrocytes; N: nucleus.