Figure 1.

A. The Organ-to-blood ratio for 10-150 µg labeled hu11B6 at 72h, uptake in the studied normal organs do not seem to change with increasing antibody amount up to 150 µg. B. The Tumor-to-blood ratio for 10-150 µg labeled hu11B6 at 72h, the tumor to blood ratio varies and seem to be lower at higher amounts of antibody, possibly because of competitive inhibition, however the variation is not statistically significant (p = 0.07). C. The Biokinetics of 177Lu-hu11B6 (20-30 µg). Tumor uptake increased up to 1 w p.i. Generally, normal organs had far less accumulation of the tracer compared to tumor, except for the submandibular glands (as a cross-reaction between human hK2 and a species specific kallikrein found in rodent salivary glands). D. Organ-to-blood ratio for ¹⁷⁷Lu-hu11B6 versus time derived from data in Figure 1C.