A. Kaplan-Meier survival curve for the therapy and control groups. Square:
177Lu-hu11B6, group A, with a median survival of 19 days. Triangle: 177Lu-hu11B6, group B, uncensored (all animals), median survival 77 days; Cross: 177Lu-hu11B6, group B, censored with a median survival beyond 120 days; Stars: unlabeled hu11B6 median survival 44 days; Circle: 177Lu-non-specific mAb median survival 33 days; Diamond: Vehicle median survival 23 days. B. Hematopoietic toxicity for the therapy group NMRI-foxn1nu/foxn1nu. From dosimetry the absorbed dose to bone marrow was estimated to 7.2-8.8 Gy showing a nadir at about 12 days for white blood cells and 18 days for red blood cells where after recovery is seen. The absorbed dose to the tumor in this group was estimated to 56-68 Gy.