Figure 3. Intravenous vaccinia virus (VV)-induced CD8⁺ T cells are maintained normally in Itgb6^−/−Itgb8^ΔKC mice.

Splenic cells at the indicated time following intravenous VV infection in WT or Itgb6^−/−Itgb8^ΔKC mice were analyzed for KLRG1⁻CD127⁺ memory precursors and KLRG1⁺CD127⁻ terminal effectors by flow cytometry. (A) Representative plots gated on B8R⁺ cells are shown. (B) Total number of B8R⁺ cells, and (C) frequency (top panels) and total number (bottom panels) of KLRG1⁻CD127⁺ or KLRG1⁺CD127⁻ B8R⁺ cells are shown. Data are representative of two separate experiments with at least four mice per each time point. Data are means ± s.e.m.