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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1203–1211. doi: 10.1161/ATVBAHA.119.312682

Figure 3. Sinusoidal variation in L-FMC, MDA, ET-1, SBP and DBP.

Figure 3.

L-FMC (n = 14, panel A) displays a sinusoidal profile with a trough during the subjective night and a peak in the afternoon. Plasma levels of MDA (n = 16, panel B) and ET-1 (n = 16, panel C) displays sinusoidal variation with a trough during the subjective night and a peak around noon. Systolic BP (n = 21, panel D) and diastolic BP (n = 21, panel E) are rhythmic and sinusoidal with a trough during the biological night and a peak in the evening. Grey shaded area represents habitual sleep time (~11 PM- ~7 AM) in our participants. Circadian model is plotted from the cosinor analyses. Raw observed values are binned by circadian phase within subject and then averaged within group, and plotted as mean ± SEM.