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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2019 Apr 26;46(3):305–318. doi: 10.1007/s10928-019-09639-2

Figure-7:

Figure-7:

Model simulated relationship for relative (percentage) contribution of renal filtration and lysosomal degradation pathways towards the elimination of different size proteins. Solid line represents renal filtration and dashed line represents lysosomal degradation.