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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2019 Apr 26;46(3):305–318. doi: 10.1007/s10928-019-09639-2

Table-3.

Percentage prediction error (%PE) values for different size proteins.

%PE based on AUC0-t
Nanobody (13 kDa) 22.7
scFv (27 kDa) 54.9
Fab (50 kDa) 130
Diabody (50 kDa) −21.9
ScFv2 (55 kDa) −9.06
Minibody (80 kDa) −15.9
F(ab)2 (100 kDa) 135
IgG in FcRn KO mice (150 kDa) −53.7