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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Mech Dev. 2019 Apr 8;157:1–9. doi: 10.1016/j.mod.2019.04.001

Figure 4:

Figure 4:

Gene expression and pathway analysis of nco embryos. (A) Ingenuity Pathway Analysis shows the top up-regulated and down-regulated pathways, which are eNOS Signaling and Endothelin-1 Signaling, respectively. Positive z-score indicated increased mRNA levels. Negative z-score indicates decreased mRNA levels. No change in mRNA levels results in a z-score of zero. (B) Differential gene expression in the top up-regulated genes. (C) Differential gene expression in the top down-regulated genes. (**, expressed in adult zebrafish mechanosensory hair cells) [32].