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. 2019 Apr 2;27(4):703–712.e3. doi: 10.1016/j.str.2018.12.007

Figure 5.

Figure 5

G-Protein Coupling Leads to Increase in the Strength of the Allosteric Coupling

Allosteric communication pipelines from the EC region of the receptor to the G protein coupling region in the NECA-bound A2AR in various conformational states. The thickness of the pipelines shown is proportional to the strength of correlation in torsional angle motion of residues involved in this pipeline of communication.