Table 2.
Sensitivity and specificity values of the pooled data from studies of nitrite stick testing, according to age range and the evidence quality
| Evidence level | Studies of infants | Studies of older children | Difference by age | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Studies | Cases | Sensitivity or specificity | Studies | Cases | Sensitivity or specificity | Contingency table analysis | |||
| (n) | (References) | (n) | (n) | (References) | (n) | (p value) | |||
| Sensitivity | |||||||||
| Level 1 only | 2 | [14, 19] | 30 | 0.23 | 5 | [12, 14, 27–29] | 129 | 0.81 | < 0.0001F |
| Levels 1 and 2 | 10 | [14, 16, 19–26] | 1284 | 0.38 | 7 | [12, 14, 16, 27–30] | 153 | 0.78 | < 0.0001F |
| All 3 levels | 11 | [14, 16, 18–26] | 1321 | 0.38 | 9 | [12, 14, 16, 17, 27–30] | 259 | 0.72 | < 0.0001F |
| Specificity | |||||||||
| Level 1 | 10 | [14, 16, 19, 22–26, 31] | 1783 | 0.990 | 7 | [14, 16, 17, 27–30] | 5952 | 0.996 | 0.002χ |
FFisher’s exact test. χChi-square test