Table 2.

Changes of parameters of LA function as evaluated by conventional echocardiography following the ablation procedures.

Variables	Groups	Baseline	1 week	2 weeks	3 weeks	4 weeks	2 months	3 months	6 months	9 months	12 months	p for groups
Peak A-wave velocity (cm/s)	Freeze	74.62 ± 20.33	66.54 ± 19.10	72.51 ± 22.30	68.37 ± 20.34	69.76 ± 22.65	70.23 ± 23.53	75.23 ± 20.94	73.55 ± 18.46	77.00 ± 17.20	77.33 ± 17.64	0.220
	Freeze 3D	82.12 ± 21.48	71.98 ± 22.66	73.17 ± 25.54	74.13 ± 19.54	70.43 ± 19.87	75.57 ± 19.30	74.85 ± 21.16	72.50 ± 22.56	64.00 ± 16.46	61.40 ± 10.26
	RF	73.37 ± 19.97	65.99 ± 17.31	67.84 ± 17.62	69.76 ± 21.14	67.96 ± 19.34	68.88 ± 20.48	68.67 ± 20.04	71.02 ± 19.16	70.20 ± 18.46	70.58 ± 15.70
	p for time	—	<0.001	<0.001	<0.001	<0.001	<0.001	0.006	0.002	0.061	0.961
Peak E-wave velocity (cm/s)	Freeze	69.50 ± 21.80	74.07 ± 22.71	74.26 ± 21.81	70.83 ± 18.28	69.92 ± 18.60	74.50 ± 23.27	75.51 ± 20.37	73.95 ± 19.32	71.95 ± 26.08	75.61 ± 17.31	0.237
	Freeze 3D	67.72 ± 19.82	64.14 ± 18.12	72.69 ± 21.93	68.64 ± 18.49	70.88 ± 25.10	71.43 ± 22.79	62.05 ± 15.22	69.16 ± 22.17	56.57 ± 8.52	60.00 ± 7.52
	RF	68.86 ± 18.98	72.61 ± 19.21	70.59 ± 21.46	69.78 ± 18.55	70.62 ± 21.79	69.90 ± 20.90	68.81 ± 19.69	70.93 ± 17.43	69.95 ± 18.23	70.11 ± 17.20
	p for time	—	0.518	0.222	0.986	0.887	0.211	0.928	0.501	0.999	0.164
LAEF (%)	Freeze	48.26 ± 17.50	48.70 ± 13.70	52.22 ± 13.68	54.06 ± 12.20	52.52 ± 15.21	54.41 ± 14.76	55.54 ± 15.63	57.19 ± 12.98	58.28 ± 8.16	60.69 ± 7.52	0.131
	Freeze 3D	58.21 ± 14.78	52.75 ± 11.73	56.00 ± 12.05	55.28 ± 12.64	58.48 ± 11.21	57.95 ± 12.33	57.18 ± 11.25	57.47 ± 8.44	62.14 ± 8.67	60.50 ± 8.54
	RF	53.42 ± 13.90	51.51 ± 11.76	53.51 ± 11.62	53.49 ± 10.51	53.24 ± 12.91	54.43 ± 12.20	55.34 ± 11.05	54.06 ± 13.27	54.39 ± 10.22	55.62 ± 13.25
	p for time	—	0.124	1.000	0.99	0.898	0.567	0.162	0.178	0.304	0.112
LA anteroposterior dimension (mm)	Freeze	35.80 ± 4.42	36.11 ± 3.46	35.65 ± 3.53	36.04 ± 3.79	35.76 ± 3.46	35.28 ± 3.28	35.91 ± 3.11	36.27 ± 3.49	34.60 ± 2.19	35.35 ± 5.11	0.608
	Freeze 3D	34.52 ± 4.25	35.53 ± 4.48	35.66 ± 4.16	35.69 ± 4.47	35.49 ± 4.19	35.41 ± 4.47	35.79 ± 4.76	36.58 ± 4.87	33.50 ± 3.89	33.60 ± 3.29
	RF	35.67 ± 5.05	36.58 ± 4.73	36.06 ± 4.17	35.81 ± 4.42	35.39 ± 4.17	35.31 ± 4.29	35.44 ± 4.57	35.19 ± 3.95	34.55 ± 3.49	35.58 ± 6.92
	p for time	—	0.620	0.870	0.283	0.940	0.997	1.000	0.973	1.000	1.000
LA transverse dimension (mm)	Freeze	40.87 ± 6.93	38.67 ± 4.86	38.25 ± 6.48	39.00 ± 4.88	37.98 ± 5.03	37.57 ± 3.81	38.73 ± 3.79	37.26 ± 4.32	36.70 ± 2.79	36.56 ± 3.48	0.209
	Freeze 3D	35.31 ± 3.71	36.62 ± 3.74	36.71 ± 3.30	36.77 ± 4.46	38.13 ± 6.98	37.24 ± 4.03	37.65 ± 5.16	38.53 ± 4.29	36.86 ± 2.61	37.80 ± 2.39
	RF	38.66 ± 7.80	39.88 ± 8.09	39.11 ± 4.93	38.35 ± 4.56	38.65 ± 5.26	38.27 ± 4.61	37.81 ± 5.18	37.43 ± 3.48	37.24 ± 4.09	37.57 ± 6.12
	p for time	—	1.000	0.984	0.866	1.000	0.444	0.834	0.233	0.325	0.505
LA vertical dimension (mm)	Freeze	55.63 ± 7.65	55.57 ± 6.20	56.49 ± 6.44	56.48 ± 6.87	56.18 ± 6.31	56.68 ± 6.25	56.48 ± 6.20	56.44 ± 5.32	54.00 ± 3.24	55.39 ± 5.01	0.369
	Freeze 3D	53.63 ± 5.62	54.67 ± 6.12	54.80 ± 5.99	54.36 ± 6.75	54.06 ± 7.56	53.95 ± 6.25	53.85 ± 6.40	54.47 ± 5.72	50.43 ± 5.06	54.40 ± 7.50
	RF	53.72 ± 6.44	54.82 ± 5.88	54.43 ± 5.13	54.30 ± 5.93	53.71 ± 5.91	52.30 ± 6.25	52.87 ± 5.79	53.31 ± 6.17	52.50 ± 5.50	52.61 ± 6.49
	p for time	—	0.411	0.318	0.455	1.000	0.999	0.975	1.000	0.986	1.000

p for groups indicates the p values for the comparisons of the temporal changes of related parameters among the three ablation groups.

p for time indicates the p values for the comparisons for the related parameters to their baseline values at individual follow-up time point with the combination of the three ablation groups.