Fig. 7.

Assessment of the safety of acGM-1.8 in vivo. a acGM-1.8, or four classical TLR ligands: LPS, MPLA, Poly (I:C) and Pam₃CSK₄, was intraperitoneally injected to mice at the same dose. The survival rate was calculated after 24 h of injection; n = 10. b Measurement of the key biochemical parameters, including creatine kinase (CK), lactic dehydrogenase (LDH), blood urea nitrogen (BUN), and alanine transaminase (ALT), in the serum of the mice alive after injected with PBS, Pam₃CSK₄, or acGM-1.8 (20 mg/Kg); *P < 0.05 versus the PBS treatment; n = 5