TABLE 2.
Heterodimerization of VapC-1 mutants with the wild-type VapB-1 antitoxin
| Construct | Heterodimerization of LexA DBD fusion in SU202 (Miller units) |
|
|---|---|---|
| Avg | ±SD | |
| Control vector | 1,813.4 | 130.0 |
| VapC-1 D6N | 37.9 | 11.5 |
| VapC-1 D99N | 360.5 | 30.6 |
| VapC-1 D6N D99N | 56.0 | 6.0 |
| VapC-1 E43Q | 202.2 | 18.9 |
| VapC-1 E43Q D99N | 113.3 | 5.5 |
| VapC-1 E120Q | 167.3 | 11.6 |
| VapC-1 wild type | 190.4 | 6.4 |