Figure 4.

Examples of ELAI-processed LA-ICP-MS element images. (A) The distribution of copper (Cu), iron (Fe) and carbon (C) was imaged by LA-ICP-MS in a cryosection prepared from a brain of wild-type mice. The final measurements were visualized with the open source software ELAI in advanced red (rainbow) scale, red (rainbow) scale, or grey scale. Please note that the different coloration codes in ELAI permit visualization of measured LA-ICP-MS data in a large bandwidth. Details about the freely available ELAI software package, which was developed in our laboratory, were formerly published elsewhere (39).