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. Author manuscript; available in PMC: 2020 Jan 29.
Published in final edited form as: Biochemistry. 2018 Dec 18;58(4):199–213. doi: 10.1021/acs.biochem.8b01090

Figure 9.

Figure 9

PCA plot of PreQ1 U9 and FR U9 BFU constructs with and without a ligand. Also, U25 and G33 TAR BFU constructs cluster for bulge and hairpin secondary structures, respectively.221