Table 2. Multivariate analysis for occult pathological N upstaging and occult pathological N2 upstaging.
| Variables | For occult pathologic N upstaging | For occult pathologic N2 upstaging | |||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| Age | N/A | 0.124 | N/A | 0.224 | |
| Sex | N/A | 0.144 | N/A | 0.525 | |
| Smoking index | N/A | 0.322 | N/A | 0.927 | |
| Tumor side | N/A | 0.875 | N/A | 0.746 | |
| Tumor localization | N/A | 0.691 | N/A | 0.515 | |
| Nodule type | N/A | 0.722 | N/A | 0.947 | |
| Tumor SUVmax | N/A | 0.243 | N/A | 0.262 | |
| CEA | 3.981 (1.548–10.24) | 0.004 | N/A | 0.132 | |
| Whole tumor size | N/A | 0.766 | N/A | 0.792 | |
| Solid tumor size | 14.02 (4.517–43.50) | <0.001 | 10.80(2.945-39.60) | <0.001 | |
SUVmax, maximal standardized uptake value; CEA, carcinoembryonic antigen; smoking index, the average root number per day multiplied by smoking years; CI, confidence interval.