Table 4. Association of pathological subtypes with occult nodal metastasis and occult mediastinal nodal metastasis.
| Histologic subtype | Total | Occult nodal metastasis | Occult mediastinal nodal metastasis | |||||
|---|---|---|---|---|---|---|---|---|
| pN0 (%) | pN+ (%) | P | pN0 + pN1 (%) | pN2 (%) | P | |||
| Subtype [1] | 0.001 | 0.017 | ||||||
| Papillary-predominant | 154 | 137 (89.0) | 17 (11.0) | 146 (94.8) | 8 (5.2) | |||
| Solid-predominant | 7 | 5 (71.4) | 2 (28.6) | 5 (71.4) | 2 (28.6) | |||
| Micropapillary-predominant | 1 | 0 (0) | 1 (100.0) | 1 (100.0) | 0 (0) | |||
| Other subtypes | 37 | 37 (100.0) | 0 (0) | 37 (100.0) | 0 (0) | |||
| Subtype [2] | 0.273 | 0.105 | ||||||
| Solid component (+) | 24 | 20 (83.3) | 4 (16.7) | 21 (87.5) | 3 (12.5) | |||
| Solid component (−) | 175 | 159 (90.9) | 16 (9.1) | 168 (96.0) | 7 (4.0) | |||
| Subtype [3] | 0.007 | 0.013 | ||||||
| Micropapillary component (+) | 33 | 25 (75.8) | 8 (24.2) | 28 (84.8) | 5 (15.2) | |||
| Micropapillary component (−) | 166 | 154 (92.8) | 12 (7.2) | 161 (97.0) | 5 (3.0) | |||
Other subtypes (37 cases) included adenocarcinoma in situ (4 cases), minimally invasive (8 cases), invasive mucinous (4 cases), enteric (2 cases), lepidic predominant (12 cases) and acinar predominant (7 cases).