Table 4. The concentrations of TF, TFPI, and PAI-1 ($\overline{x}\pm s$).

Variables	Group	T1	T2	T3	T4	Sum	F	P
TF (ng/mL)
Serum	A	11.16±4.55	9.36±3.90	24.46±6.67	32.24±8.00	19.30±11.21	96.09	<0.001
	C	3.63±1.39	3.05±1.56	14.01±2.80	15.46±5.80	9.04±6.65	91.61	<0.001
	Sum	7.75±5.13	6.50±4.39	19.73±7.42	24.64±10.97	14.60±10.76	134.23a	<0.001a
	t	8.45	7.97	7.66	8.57	133.67a	(F=8.57, P<0.001)b
	P	<0.001	<0.001	<0.001	<0.001	<0.001a
BALF	A	–	5.53±2.61	6.51±2.69	–	6.02±2.67	2.00	0.163
	C	–	2.18±0.98	2.60±1.37	–	2.39±1.20	1.53	0.222
	Sum	–	4.01±2.64	4.74±2.93	–	4.62±2.86	3.32a	0.074a
	t	–	6.38	3.69	–	68.14a	(F=0.52, P=0.474)b
	P	–	<0.001	0.001	–	<0.001a
TFPI (ng/mL)
Serum	A	148.06±26.61	151.19±27.55	216.29±65.84	226.04±73.39	185.40±63.47	17.87	<0.001
	C	103.67±15.59	105.65±14.45	170.53±45.97	186.42±37.58	141.57±48.70	44.87	<0.001
	Sum	127.96±31.41	130.57±32.02	195.57±61.62	208.10±62.62	165.55±61.17	58.97a	<0.001a
	t	4.81	5.14	2.49	3.33	31.98a	(F=0.07, P=0.944)b
	P	<0.001	<0.001	0.016	0.002	<0.001a
BALF	A	–	67.12±16.90	66.65±21.41	–	66.89±19.12	0.01	0.927
	C	–	36.89±8.66	40.96±14.16	–	38.93±11.80	1.45	0.235
	Sum	–	53.43±20.44	55.02±22.41	–	54.22±21.36	1.04a	0.313a
	t	–	3.72	2.44	–	45.58a	(F=1.65, P=0.205)b
	P	–	<0.001	0.018	–	<0.001 a
PAI-1 (pg/mL)
Serum	A	0.88±0.27	0.94±0.23	1.82±0.25	1.87±0.29	1.38±0.54	123.76	<0.001
	C	0.54±0.13	0.56±0.13	1.03±0.23	1.08±0.26	0.80±0.32	53.01	<0.001
	Sum	0.73±0.28	0.76± 0.27	1.46±0.46	1.51±0.48	1.17±0.54	197.81a	<0.001a
	t	5.66	5.38	6.70	6.70	213.88 a	(F=17.79, P=0.944)b
	P	<0.001	<0.001	<0.001	<0.001	<0.001 a
BALF	A	–	5.87±1.87	8.04±2.14	–	6.95±2.28	17.01	<0.001
	C	–	1.95±0.79	3.93±1.11	–	3.11±1.27	35.36	<0.001
	Sum	–	4.09±2.46	6.24±2.65	–	5.21±2.69	83.11a	<0.001a
	t	–	10.21	3.81	–	107.95a	(F=0.18, P=0.674)b
	P	–	<0.001	<0.001	–	<0.001a

^a, F statistic and P value of the main effect; ^b, F statistic and P value of crossover effect. TF, tissue factor; TFPI, tissue factor pathway inhibitor; PAI-1, plasminogen activator inhibitor-1; BALF, bronchoalveolar lavage fluid.