Table 4. Demographic and clinical characteristics of the COPD patients who were reclassified from GOLD group D to B and the COPD patients remaining in group D.
| Subjects | DB (N=285) | DD (N=619) | P value |
|---|---|---|---|
| Age (years), mean ± SD | 61.6±8.1 | 63.1±8.4 | 0.009 |
| Male, n (%) | 261 (91.6) | 564 (91.1) | 0.818 |
| BMI (kg/m2), mean ± SD | 21.9±3.4 | 21.9±3.4 | 0.957 |
| Smoking pack-years* | 30.0 (30.0) | 30.0 (30.0) | 0.341 |
| FEV1% predicted, mean ± SD | 36.9±8.7 | 46.5±17.5 | <0.001 |
| FEV1/FVC, mean ± SD | 40.6±9.8 | 46.2±11.7 | <0.001 |
| mMRC, n (%) | 0.013 | ||
| 0 | 9 (3.2) | 16 (2.6) | |
| 1 | 66 (23.2) | 92 (14.9) | |
| 2 | 102 (35.8) | 238 (38.4) | |
| 3 | 89 (31.2) | 229 (37.0) | |
| 4 | 19 (6.7) | 44 (7.1) | |
| CAT, n (%) | 0.001 | ||
| 0–10 | 22 (7.7) | 43 (6.9) | |
| 11–20 | 196 (68.8) | 382 (61.7) | |
| 21–30 | 63 (22.1) | 180 (29.1) | |
| 31–40 | 4 (1.4) | 14 (2.3) |
*, Non-normal distribution data were expressed as median (interquartile range). DB, patients switched from group D to B; DD, patients remaining in group D; SD, standard deviation; BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; mMRC, modified Medical Research Council; CAT, COPD Assessment Test; COPD, chronic obstructive pulmonary disease; GOLD, Global Initiative for Chronic Obstructive Pulmonary Disease.