Table 3. Comparison of ProGRP and NSE for pathology and histological pathology.

Tumor markers	Stage I–II				Stage III				Stage IV
	Other lung tumors	SCLC	Concordance (%)		Other lung tumors	SCLC	Concordance (%)		Other lung tumors	SCLC	Concordance (%)
ProGRPa			30.8				81.5				85.2
Other lung tumorsb	2,649	5			1,390	45			1,782	45
SCLC	224	57			50	265			31	261
ProGRP ≥66 ng/L			52.1				80.0				76.4
Other lung tumors	2,790	9			1,380	44			1,718	38
SCLC	83	53			60	266			95	268
ProGRP ≥300 ng/L			55.3				73.0				80.8
Other lung tumors	2,868	36			1,427	108			1,798	77
SCLC	5	26			13	202			15	229

^a, ProGRP criteria in stage I–II, III and IV are 56, 71 and 99 ng/L, respectively; ^b, other lung tumors. ProGRP, roles of gastrin-releasing peptide; NSE, neuron-specific enolase; SCLC, small cell lung cancer.