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. 2019 Apr;11(4):1182–1189. doi: 10.21037/jtd.2019.04.29

Table S3. Distribution of tumor markers in different stages of NSCLC and NEC.

Variable Median Cut-off
NSCLC NEC
ProGRP (ng/L)
   I 35.5 125.4 56.0
   II 35.3 183.8 54.0
   I–II 35.0 144.6 54.0
   III 35.0 559.1 64.0
   IV 34.5 1,294.2 99.0
NSE (µg/L)
   I 11.7 14.0 13.0
   II 13.0 16.5 16.0
   III 13.5 28.5 18.0
   IV 14.8 52.2 26.0

NSCLC, non-small cell lung cancer; NEC, neuro-endocrine carcinoma; ProGRP, roles of gastrin-releasing peptide; NSE, neuron-specific enolase.