Table S4. Comparison of the concordance rate of cutoff values in different stages in diagnosis of SCLC.

Variable	ProGRP ≥66 ng/L				ProGRP ≥300 ng/L
	Consistent	Inconsistent	P		Consistent	Inconsistent	P
ProGRP ≥56 ng/L			<0.001				<0.001
Consistent	2,702	4			2,663	40
Inconsistent	141	88			210	22
ProGRP ≥71 ng/L			<0.001				<0.001
Consistent	1,650	10			1,592	63
Inconsistent	1	89			37	58
ProGRP ≥99 ng/L			<0.001				<0.001
Consistent	2,079	64			2,011	32
Inconsistent	7	69			16	60

Consistent, the pathological type determined by tumor marker was same as the results of living tissue; Inconsistent, the pathological type determined by tumor marker was different from the results of living tissue. SCLC, small cell lung cancer; ProGRP, roles of gastrin-releasing peptide.