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. 2019 Apr;11(4):1106–1116. doi: 10.21037/jtd.2019.04.46

Table S2. Final multivariate model after backwards selection using BIC criteria. Variables considered: clinical stage, smoking status, tumor grade, mediastinal staging, pathologic node status, hemoglobin levels, DLCO, history of hypertension, use of adjuvant chemotherapy, SUVmax, SUVpeak, SUVmean, Homogeneity, Entropy-GLCM.

Metric DFS (Nevents=34) OS (Nevents=26)
HR (95% CI) P value HR (95% CI) P value
Hemoglobin 0.76 (0.61–0.94) 0.01
DLCO 0.95 (0.93–0.98) 0.005 0.96 (0.94–0.99) 0.005
Hypertension 2.83 (1.29–6.22) 0.01 2.97 (1.17–7.52) 0.02
Tumor grade (mod/poor) 8.9 (1.9–41) 0.005
Entropy-GLCM 0.65 (0.49–0.87) 0.004 0.60 (0.45–0.81) 0.0007
Adjuvant chemotherapy 1.19 (0.87–1.64) 0.28 4.79 (1.9–12) 0.09

DLCO, diffusing capacity of the lungs for carbon monoxide; GLCM, grey-level co-occurrence matrix.