Table 3. EGFR mutation status concordance between matched tissue/cytology and plasma samples (tissue/cytology and plasma evaluable populations).
Adjusted parameters | Matched tissue/cytology samples (N=126) | ||
---|---|---|---|
n/N | Percentage | Exact 95% CI | |
Concordance rate | 121/126 | 96.0 | 91.0–98.7 |
Sensitivity | 9/14 | 64.3 | 35.1–87.2 |
Specificity | 112/112 | 100.0 | 96.8–100.0 |
PPV | 9/9 | 100.0 | 66.4–100.0 |
NPV | 112/117 | 95.7 | 90.3–98.6 |
CI, confidence interval; EGFR, epidermal growth factor receptor; NPV, negative predictive value; PPV, positive predictive value.