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. 2019 Apr;11(4):1370–1378. doi: 10.21037/jtd.2019.03.95

Table 3. EGFR mutation status concordance between matched tissue/cytology and plasma samples (tissue/cytology and plasma evaluable populations).

Adjusted parameters Matched tissue/cytology samples (N=126)
n/N Percentage Exact 95% CI
Concordance rate 121/126 96.0 91.0–98.7
Sensitivity 9/14 64.3 35.1–87.2
Specificity 112/112 100.0 96.8–100.0
PPV 9/9 100.0 66.4–100.0
NPV 112/117 95.7 90.3–98.6

CI, confidence interval; EGFR, epidermal growth factor receptor; NPV, negative predictive value; PPV, positive predictive value.