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. 2019 Apr 9;116(10):1931–1940. doi: 10.1016/j.bpj.2019.04.002

Table 1.

The Estimated Number of Lipids in the Central Cavity of HTL, Estimated by Three Different Methods

Method Estimated Number of Lipids in the Core Shape of the Lipid Core (see Fig. 7)
CG MD 9.4 ± 0.8 lipid monolayer
SANS, I(0) 10 ± 14a no shape assumed
SANS, fitting 8–29 lipid bilayer with cylindrical shape
a

The number of lipids determined from the I(0) alone was affected by protein aggregation (see main text). These aggregations were taken into account in the fitting process.