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Ancestry clustering and eQTL methodology. A. Genotype clustering of samples from PPP and OD samples confirmed European descent of subjects, compared to the 1,000 genomes. B. An overview of the methodology utilized to obtain eQTLs from islets of OD and PPP subjects were isolated by limited digestion from OD material and by LCM from PPP material. Acis-window of 500 kb was used with adjustment on gender and age and a false discovery rate (FDR) of <5% was used as a cut-off.
