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. 2019 Mar 18;24:98–107. doi: 10.1016/j.molmet.2019.03.004

Figure 4.

Figure 4

Summary of eQTL genes with relevance to T2D. A schematic of a representative pancreatic beta cell, with identified genes annotated to their known sub-cellular localization using gene ontology. These genes include overlapping GWAS genes (black), eQTLs in LD with GWAS loci (asterisks), eQTL genes from the PPP dataset that were differentially expressed in T2D (red) or associated with HbA1c (pink), consistent in directional effect with eQTLs. (Figure was illustrated using app.biorender.io).