Table 2.
GWAS T2D and glycaemic genes identified in eQTL study.
| Gene | Gene Name | Disease/Trait | PPP | OD | Fadista et al., 2014 | Van de Bunt et al., 2015 |
|---|---|---|---|---|---|---|
| ABO | ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase | Disposition index and soluble E-selectin levels | Y | Y | Y | |
| ADCY5 | Adenylate Cyclase 5 | Type 2 diabetes; fasting glucose-related traits | Y | Y | ||
| AP3S2 | Adaptor Related Protein Complex 3 Sigma 2 Subunit | Type 2 diabetes | Y | Y | Y | Y |
| GPSM1 | G Protein Signaling Modulator 1 | Type 2 diabetes | Y | |||
| IGF1R | Insulin Like Growth Factor 1 Receptor | Fasting plasma glucose | Y | Y | ||
| MAEA | Macrophage Erythroblast Attacher | Type 2 diabetes | Y | |||
| SSR1 | Signal Sequence Receptor Subunit 1 | Type 2 diabetes | Y | |||
| TLE4 | Transducin Like Enhancer Of Split 4 | Type 2 diabetes | Y | |||
| TPCN2 | Two Pore Segment Channel 2 | Type 2 diabetes | Y | Y | Y | |
| TMEM163 | Transmembrane Protein 163 | Type 2 diabetes | Y | Y | ||
| UBE2Z | Ubiquitin Conjugating Enzyme E2 Z | Type 2 diabetes | Y | Y | ||
| UHRF1BP1 | UHRF1 Binding Protein 1 | Fasting insulin-related traits | Y |
Y=Yes