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. 2019 Mar 21;24:64–79. doi: 10.1016/j.molmet.2019.03.008

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

FTH is essential to support energy expenditure. Cumulative (A,B) Energy expenditure, (C,D) Respiratory Quotient, and (E,F) Locomotor Activity of Fth^fl/fl (n = 14) and Fth^R26Δ/Δ (n = 8), monitored from days 6–8, after the first tamoxifen administration. Data are represented as mean ± SD, pooled from 3 independent experiments. Average (G), daily (H), and cumulative (I) food intake of Fth^fl/fl (n = 8) and Fth^R26Δ/Δ (n = 6), monitored from days 6–8, after the first tamoxifen administration. Data is represented as mean ± SD, from 2 independent experiments. NS: non-significant, **P < 0.01, ***P < 0.001.