Table 2.
Cancer and non-cancer conversion rates by indication for referral in adult patients referred to a one-stop clinic with symptoms that could be indicative of cancer
| Indication for one-stop referral | Conversion rates | ||||||
|---|---|---|---|---|---|---|---|
| Cancer | Non-cancer diagnoses | ||||||
| Studies (N) | Range (%) | Pooled % (95% CI) | Studies (N) | Range % | Pooled % (95% CI) | ||
| Abnormal vaginal bleeding | One-stop | 6 | 1.3–5.2 | 3.7 (2.7 – 4.9) | 5 | 4.2 – 58.1 | 30.3 (17.0 – 45.5) |
| Multi-stop | 1 | 5.9 | — | 1 | 17.7 | — | |
| Breast symptoms | One-stop | 6 | 5.3–16.1 | 8.5 (6.8–10.4) | 2 | 68.9–90.0 | 81.5 (78.3–84.6) |
| Multi-stop | 2 | 9.1–12.3 | 10.2 (7.8–12.8)* | 1 | 64.5 | — | |
| Lower gastrointestinal symptoms | 3 | 0.9–3.2 | 1.7 (0.5–3.5) | 3 | 59.2–96.8 | 82.1 (61.8–95.8) | |
| Elevated PSA | 3 | 31.1–55.5 | 42.8 (28.5–57.7) | 1 | 24 | — | |
| Haematuria | 1 | 14.2 | — | 1 | 28.3 | — | |
| Enlarged lymph node | 1 | 19.5 | — | 1 | 80.5 | — | |
| Neck lump | 1 | 16.2 | — | 1 | 64.3 | — | |
| Testicular symptoms | 3 | 1.0–5.6 | 3.2 (0.9–6.7) | 3 | 15.0–75.7 | 49.5 (14.0–85.4) | |
| Upper gastrointestinal symptoms | 2 | 3.3–7 | 3.9 (2.3–5.9) | 2 | 41.2–72.0 | 48.2 (43.6–52.7) | |
*P = 0.28.