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. 2019 May 15;10:580. doi: 10.3389/fphys.2019.00580

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Copyright © 2019 Lopez-Perez, Sebastian, Izquierdo, Ruiz, Bishop and Ferrero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Segmentation process from short-axis DE-MRI slices of the heterogeneous remodeling caused by MI, including infarct scar and BZ. Left panel shows the first step that involves the manual delineation of remote ROI (region-of-interest) (green) and infarcted ROI (yellow) within the LV myocardium ROI (red), also displaying the RV myocardium ROI (cyan). Right panel shows the segmentation for infarct scar (purple) and BZ (yellow) resulting from the application within the infarcted ROI of thresholds determined by SD method from the remote ROI of each slice. (B) 3D representation of the MI reconstructed from DE-MRI images, showing posterior views of the 3D surface model of ventricles (rendered with transparency) along with those hexahedral elements of volume mesh labeled as infarct scar (red) and BZ (blue).