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. 2019 May 15;10:580. doi: 10.3389/fphys.2019.00580

Figure 6.

Figure 6

Comparison between APs generated by the original version of ten Tusscher model (ten Tusscher and Panfilov, 2006), used in our simulations for healthy myocardium, and APs resulting from our modified version of such model for the remodeled BZ. Upper row shows APs from a simulation with a single isolated cell, after stabilizing the model at a BCL of 800 ms, while the lower row displays APs obtained for a cell embedded in a 3D tissue (i.e., surrounded by other cells and electrically coupled to them) exclusively composed of remodeled myocytes.