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. 2019 May 15;10:580. doi: 10.3389/fphys.2019.00580

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Copyright © 2019 Lopez-Perez, Sebastian, Izquierdo, Ruiz, Bishop and Ferrero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activation map for CARTO-derived sinus activation, corresponding to the sixth heartbeat simulated with the ventricular model with ER and 10% fibrosis in BZ (model #6). Top row shows an anterior (A) and a posterior (B) view of a coronal cross-section (four-chamber plane) of the ventricular model, showing the activation on the endocardial surfaces. Bottom row also displays anterior (C) and posterior (D) views of the whole model, showing the activation at epicardial level. Black regions correspond to not activated tissue (not depolarized) due to fibrosis accumulation. Gray region represents the infarct scar, modeled as non-conducting tissue.