Table 1.
Different versions of the computational model of ventricles according to the kind of remodeling included in the BZ (ER and/or fibrosis) and results of in-silico VT inducibility tests performed with CVs in BZ reduced by 75% with respect to the healthy tissue.
| Model version | Fibrosis in BZ (%) | ER in BZ | Pacing site | ||
|---|---|---|---|---|---|
| endo#1 | epi#1 | epi#2 | |||
| #1 | 0 | NO | no VT | no VT | no VT |
| #2 | 10 | no VT | no VT | no VT | |
| #3 | 20 | no VT | no VT | no VT | |
| #4 | 30 | no VT | S3−290 ms 510 ms−117 bpm |
no VT | |
| #5 | 0 | YES | no VT | S2−360 ms 506 ms−118 bpm |
no VT |
| #6 | 10 | S3−370 ms 526 ms−114 bpm |
S2−360 ms 526 ms−114 bpm |
no VT | |
| #7 | 20 | S3−370 ms 520 ms−115 bpm |
S2−360 ms 520 ms−115 bpm |
no VT | |
| #8 | 30 | no VT | no VT | no VT | |
In the cases of positive VT induction, we specify the premature stimulus (S2 or S3) responsible for the unidirectional block triggering the reentrant VT and its CI, as well as the BCL and heart rate associated with the VT.