Table 1.
Clinical characteristics of PID group
| No | Sex | Age of diagnosis (month) |
Age of onset of 1st symptoms (month) |
Clinical manifestations | Diagnosis |
| 1 | M | 1.3 | 1.3 | Pneumonia, fungal infections, sibling death. | SCID (ADA) |
| 2 | F | 0.5 | 0.5 | Previous affected sibling. | SCID (JAK3) |
| 3 | M | 6 | 0.3 | Pneumonia, fungal infections. | SCID (IL7R) |
| 4 | F | 0.3 | 0.3 | Previous affected sibling, sibling death. | SCID(DCLRE1C) |
| 5 | F | 6 | 0.6 | Failure to thrive, otitis media, fungal infection. | SCID(JAK3) |
| 6 | M | 6 | 3 | Pneumonia, evidence of fungal infection, otitis media, family death due to infection. | SCID(IL2RG) |
| 7 | F | 5 | 0.2 | Pneumonia, fungal infection, sibling death. | SCID (Unident) |
| 8 | M | 3 | 0.2 | Pneumonia, fungal infection, sibling death, family death. | SCID (RAG1) |
| 9 | M | 6 | 5 | previous affected sibling, Pneumonia, fungal infection, family death, axillary lymphadenopathy after BCG vaccine, sibling death. |
SCID(RAG2) |
| 10 | M | 2 | 0.2 | Pneumonia, sepsis, Pericardial effusion, family death. | SCID (ADA) |
| 11 | F | 3 | 0.5 | Failure to thrive, Pneumonia, family death, sibling death. | SCID(Unident) |
| 12 | M | 6 | 1 | Pneumonia, fungal infection, organomegaly , sibling death. | SCID(Unident) |
| 13 | F | 3 | 2 | Pneumonia, fungal infection, deep seated abscesses. | SCID(Unidenti) |
| 14 | F | 6 | 2 | Failure to thrive, Pneumonia, fungal infection. sibling death. | SCID(Unident) |
| 15 | F | 6 | 4 | Failure to thrive, Pneumonia, evidence of fungal infection, recurrent of admission | SCID (JAK3) |
| 16 | F | 5 | 3 | Pneumonia, fungal infection, organomegaly, sibling death. | SCID(Unident) |
| 17 | M | 5 | 0.3 | Pneumonia, fungal infection, deep seated abscesses, otitis media, sepsis, organomegaly, | SCID(Unident) |
| 18 | M | 5 | 0.3 | Pneumonia, fungal infection, deep seated abscesses . | SCID(Unident) |
| 19 | F | 6 | 2 | Pneumonia, fungal infection, skin rash, siblingdeath. | Omenn syndrome |
| 20 | F | 4 | 2 | Pneumonia, fungal infection, Exfoliative skin rash. | Omenn syndrome |
| 21 | F | 6 | 4 | Failure to thrive, CNS infection, pneumonia, diarrhea and paralysis after Polio vaccine | MHC class II (RFXANK) |
| 22 | M | 6 | 1.3 | Pneumonia, fungal infection, deep seated abscesses, meningitis, sepsis, family death. | Isolated CD4 lymphopenia |
| 23 | M | 5 | 1 | Pneumonia, fungal infection, otitis media. | Hyper IgE |
| 24 | M | 5 | 1.5 | Recurrent deep seated abscesses. | CGD |
| 25 | M | 5 | 0.3 | Ulcers, delayed umbilical stump separation, severe omphalitis, Pneumonia, otitis media, organomegaly |
LAD |
| 26 | M | 5 | 0.2 | Lymphadenitis, Pneumonia, organomegaly, BCGoma, history of death in family with TB. | Unclassified PID (suspected Mendelian susceptibility to mycobacterial disease). |
SCID: Severe Combined Immunodeficiency Disorders.
HIES: Hyper Immunoglobulin E syndrome.
MHC class II: Major histocompatibility complex class II deficiency.
LAD: Leukocyte Adhesion Deficiency.
CGD: Chronic Granulomatous Disease.
CNS: Central nervous system.