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. 2019 Mar;19(1):1311–1320. doi: 10.4314/ahs.v19i1.2

Table 2.

Summary ORs and 95%CI of IL-18 gene polymorphisms and TB risk

Subgroup Genetic model Effects
model
Test of heterogeneity Test of association
I2 P OR 95% CI
−607C>A
Overall AA vs CC Random 70.2% 0.01 1.27 0.82–1.96
CA vs CC Fixed 39.7% 0.16 1.06 0.89–1.26
Dominant model Random 59.8% 0.04 1.09 0.83–1.43
Recessive model Random 52.5% 0.08 1.23 0.92–1.65
Consistent with AA vs CC Fixed 0.00% 0.80 1.01 0.77–1.31
HWE CA vs CC Fixed 0.00% 0.72 0.94 0.77–1.15
Dominant model Fixed 0.00% 0.72 0.96 0.79–1.16
Recessive model Fixed 0.00% 0.80 1.04 0.83–1.31
−137G>C
GG vs CC Fixed 2.00% 0.36 1.42 0.78–2.58
GC vs CC Fixed 0.00% 0.38 1.16 0.62–2.16
Dominant model Fixed 0.00% 0.38 1.34 0.74–2.43
Recessive model Random 78.4% 0.03 0.96 0.26–3.56