FIG 2.

MccPDI is effective against UTI E. coli and Shigella strains. (A) Competition between MccPDI-producing strain E. coli 25 and positive and negative controls (BW25113 and BW25113 ΔompF, respectively) as well as 10 other strains in M9 medium for 24 h. (B) Competition between the MccPDI producer E. coli 25 and target Shigella strains (S. flexneri 24570, S. flexneri 2457T, S. sonnei WRAIR I virulent, S. dysenteriae Newcastle 1934, and Shigella sp.) in M9 medium for 24 h. Results are expressed as the difference in mean log CFU during coculture and monoculture of the target strain (n = 3 independent replicates; error bars indicate standard errors of the means [SEM]). *, P < 0.05 compared to wild-type (BW25113) coculture based on one-way ANOVA.