Table 1.
Overview of sequences obtained from VlsE-C6 reactive single B cells with in vitro single cell stimulation.
| CDR3aa | Stimulated sample | # Sequences | Related clone HTS | V-gene | J-gene |
|---|---|---|---|---|---|
| ARVVCTGGT | Lyme8 (T1) | 1 | No | IGHV4-34 | IGHJ5 |
| ARGTRDGQ | Lyme8 (T1) | 1 | No | IGHV3-33 | IGHJ1 |
| ARGTRDGQNPEFDY | Lyme8 (T1) | 2 | Lyme8 | IGHV3-33 | IGHJ4 |
| ARADDSPSYYVNAFDL | Lyme4 (T1) | 1 | No | IGHV5-51 | IGHJ3 |
| AILWGGLGVVTPDYYYFEMDV | Lyme3 (T1 & T2) | 1 | No | IGHV1-69 | IGHJ6 |
| TRNEIQLDD | Lyme6 (T0 & T1 & T2) | 1 | No | IGHV3-49 | IGHJ4 |
| VRNHTVYVGGNCNSNPGVFDI | Lyme6 (T0 & T1 & T2) | 1 | No | IGHV3-48 | IGHJ3 |
| ARSYEYYYYYAMDV | Lyme6 (T0 & T1 & T2) | 1 | Control (1 sequence) | IGHV3-7 | IGHJ6 |