Fig. 6.

Scavenging reactive oxygen species (ROS) by N-acetylcysteine (NAC) decreases the proapoptotic effect induced by hypoxia in cardiomyocytes. Caspase-3 activity in the cardiomyocytes was determined in four treatment groups. Hypoxia+NAC group were pretreated with NAC (2.5 mM) for 30 min before exposure to hypoxia. *p < 0.05 vs normoxia group and normoxia+NAC group, respectively; # p < 0.05 vs hypoxia group. Data are the mean ± SEM. Error bars indicate SEM, p value was analyzed using post hoc Tukey’s tests. The experiment was repeated three times