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. 2019 May 22;19:479. doi: 10.1186/s12885-019-5693-2

Table 1.

Description of the vitronectin and nuclei morphometric measurements of control tissues and NB primary tumors

Parameter Median Mean SD Range Q3
Normal control tissues other than liver (n = 12)
IPP Nuclei Density 308.10 305 99.75 94.10–477.70 355
%SA 7.30 7.90 3.35 4–14 8.80
Inter. VN %SA 1.57 3.92 5.70 0.42–17 3.67
Terr. VN %SA 0.04 0.07 0.07 0–0.20 0.15
Densito VN ratio of pixels Weak 0.04 1 1.50 0–4 1.75
Moderate 2.25 10.95 13 0.06–35 22.90
Strong 1 2 2.60 0–9 2.95
H-score 20.45 46.40 52.51 0.16–163 82.50
Liver samples (n = 5)
IPP Nuclei Density 616 1846.70 2384.30 472–6051.70 3767.80
%SA 4 3.80 2.05 2–7 5.50
Inter. VN %SA 20 19 11.40 3–31 29.50
Terr. VN %SA 3 2.50 1.30 0.65–4 3.50
Densito VN ratio of pixels Weak 2.50 2.85 2.30 0.30–6 5.15
Moderate 67 64.55 8.30 50–71 69.50
Strong 12.75 13.50 2.70 10–17 16
H-score 175.80 172.60 11.60 152.25–181.35 179.55
Primary tumors (n = 91)
IPP Nuclei Density 560 1074.25 1455.80 95–6793 739
%SA 11.75 11.70 6.30 0.35–29.70 15.50
Inter. VN %SA 9.35 12.25 10.95 0.02–40.97 18.20
Terr. VN %SA 0.71 2.95 4.45 0.01–20.70 4.50
Densito VN ratio of pixels Weak 0.80 1.60 2.40 0.01–14.65 2.10
Moderate 35 36.10 24.70 0.05–88.10 56.75
Strong 3.55 12.85 17.85 0.01–61.85 20.40
H-score 110.91 112.85 78.55 1.07–257.60 183.80

Descriptors of vitronectin (VN) immunoreactivity and nuclei according to their morphometric measurements are shown. IPP: Image Pro-Plus; Densito: DensitoQuant; Inter.VN: Interterritorial VN; Terr.VN: Territorial VN. Density: number of objects/mm2; %SA: percentage of stained area. SD: Standard deviation; Q3: third quartile