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. 2019 May 9;2019:6387357. doi: 10.1155/2019/6387357

Table 2.

Mitochondrial receptors and their ligands involved in the mitophagic process.

Receptor Localization Ligands (interaction) Species Reference
ATG32 Outer mitochondrial membrane Atg8, Atg11 Yeast [22]
NIX/BNIP3L Outer mitochondrial membrane LC3 Mammals [2325]
BCL2L13 Outer mitochondrial membrane LC3 Mammals [26]
FUNDC1 Outer mitochondrial membrane LC3 Mammals [27]
Cardiolipin Mitochondrial inner membrane, any damage to mitochondria, or depolarization of its membrane results in the translocation to outer mitochondrial membrane LC3 Mammals [28]
PHB 2 Inner mitochondrial membrane LC3 Mammals [29]
Parkin Normally in the cytosol, it is translocated to the outer mitochondrial membrane upon depolarization AMBRA1, LC3 Mammals [30]
BCL2L13 Outer mitochondrial membrane LC3 Mammals [31]
FKBP8 Outer mitochondrial membrane LC3 Mammals [32]
SMURF1 Cytoplasmatic, colocalized with damaged mitochondria LC3? Mammals
BNIP3 Outer mitochondrial membrane LC3 Mammals [33]
NLRX1 Outer mitochondrial membrane LC3 Mammals [34]